Dr. Allen Seward (Robert Francis) is the new doctor at a remote Army outpost. His liberal attitudes towards Native Americans become a source of tension between him and his superiors, especially Capt. Peter Blake (Philip Carey), who regards all Native Americans as dangerous and untrustworthy. Seward's insistence on treating several local Kiowa tribespeople for malaria further enrages Blake, who deems Seward a traitor when the Kiowa join forces with the Comanches and attack the fort.