The Nickelodeon cartoon series the Wild Thornberrys gets it's first feature-length animated film directed by show creator Cathy Malkasian with a screenplay by Kate Boutilier (writer of Nickelodeon's Rugrats in Paris). The main character is 12-year-old Eliza Thornberry (voice of Lacey Chabert) a braces-and-glasses-wearing eccentric girl in an adventurous family of travelers. Due to an interaction with a shaman she has been granted the special power of communication with animals as long as she promises not to tell anyone about it. Her powers are challenged when her parents Nigel (voice of Tim Curry) and Marianne (voice of Jodi Carlisle) decide to take the family on an African safari to make a nature documentary. Also along for the trip is snobby sister Debbie (voice of Danielle Harris) feral youngster Donnie (voice of Flea from the Red Hot Chili Peppers) and pet chimpanzee Darwin (voice of Tom Kane). After her new Cheetah cub friend is stolen by poachers Eliza is determined to get involved. However the stuffy Thornberry grandparents get in the way by sending her to boarding school. It's up to Eliza and Darwin to defeat the poachers and save the cub. Also featuring the voice talents of Brenda Blethyn and Lynn Redgrave.